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So why does the source matter
These signs may indicate irritation or infection rather than a simple bruise
Janice Jin Hwang, chief of the division of endocrinology and metabolism at the University of North Carolina at Chapel Hill, explains that there are these networks of brain regions that have been very well characterized, mainly in addiction literature, that control our desire and motivation for food but also for addicting things. One reason food lights up reward pathways is that its essential for survival, says Lorenzo Leggio, an addiction researcher at the National Institute on Alcohol Abuse and Alcoholism and the National Institute on Drug Abuse
PCOS patients should also be screened for thyroid history before starting, as semaglutide is not advised with personal or family history of medullary thyroid carcinoma
The emerging consensus in 2026 is that semaglutide can be used indefinitely if clinical benefit persists and the patient and provider agree continuation is appropriate
