The phenolic-rich extracts also inhibited -amylase and -glucosidase (646)
on the supposed aggravation of COVID-19 ( more topical than ever ( The French Ministry of Health Olivier Veran embracing Micallefs hypothesis, warned the public to avoid NSAIDs like ibuprofen in case of SARS-CoV-2 infection ( On the other hand, the warning was immediately questioned ( Indeed, a closer view to NSAIDs pharmacodynamics might lead to opposite conclusions on their therapeutic value in SARS-CoV-2 infection
Authors and Reviewers Originally written in 2000 by: Jane Higdon, Ph.D
The authors further use the invasive isolates MC58 and DE13664, and the carrier isolates 711 and 275, revealing a dramatic change in the capability of crossing the Calu3 monolayer and in the number of intracellular bacteria between invasive and carrier isolates (Peters et al., 2024)
These effects are partly attributed to an endothelium-dependent vasodilator effect, primarily through activation of the eNOS-NO-soluble guanylyl cyclase (sGC) pathway, along with reductions in HR and CCB activity
