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Though this is speculative rather than evidence-based

NAD deficiency was first discovered in 1937 but has only begun to take hold in the medical community as being linked to general inflammatory disease with its supplementation being crucial to overall health and wellbeing

It is unknown whether this downregulation is the primary cause of the disorder, but it is likely to be a contributing factor

The study also opens the door for more future research about the administration routes of vitamin B12 and other vitamins

Compounding pharmacies are regulated at the state and federal levels and subject to government inspections, making them a safer option than unlicensed online vendors, said Lee