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Furthermore, 14% (66 patients) and 24% (62 patients) were nonresponders among patients with CD and UC, respectively (OR: 0.48, 95% CI: 0.330.72, P =0.001)

There is not enough evidence to conclude that smaller doses reliably produce the same clinical effects as larger doses of other forms

Our observation that MCP-1 levels were not regulated by either ACE2 inhibition or downregulation, in addition to the differential effect observed on IL-6 production, suggests that other SARS-CoV-2 receptors in endothelial cells may be involved 37, 38