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It can reduce IL-1 and IL-18 expression through the NF-B/NLRP3 pathway, lower blood glucose levels, and improve insulin sensitivity and insulin resistance ( Daotan Decoction has been shown to improve inflammatory responses, insulin resistance, and regulate lipid metabolism, but the mechanisms underlying these effects and their relationship with the gut microbiota remain unclear
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NTZ effects were dose-dependent, where the higher dose was more efficient and closer to the effect of NAC or 4-PBA