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Cell-permeable fluorescent probes like monochlorobimane (mCB) and ThiolTracker Violet also enable live-cell glutathione imaging using confocal microscopy or flow cytometry platforms

"Many are guessing that it (the Nobel Prize in Medicine) will go to the people behind GLP-1," Lars Brostrom, science editor at public broadcaster Sveriges Radio, told AFP

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Drawing parallels with the continued optimization of insulin analogues, this articles proposes that the electrostatic scaffold offers a robust framework for the continued development of next-generation GLP-1R agonists, enabling more precise and effective therapies for managing metabolic diseases