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These medicines work in two main ways: they make you feel full for longer by slowing stomach emptying, and they calm the parts of your brain that trigger cravings for comfort or enjoyment

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Therefore, in peri- and post-menopausal patients, rapid or substantial weight loss while on semaglutide may plausibly unmask or intensify GSM symptoms via endocrine and tissue-level changesalthough the specific contribution of semaglutide vs weight loss per se is not established

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Ozempic and Wegovy are proven to significantly lower those risks