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Reduced appetite often makes it difficult to maintain consistent protein intake through food alone

For weight loss, tirzepatide is usually more directly effective than TRT because it targets appetite, cravings, blood sugar, and metabolism

Endocrinology 2003

They found that even without causing weight loss, retatrutide had anti-tumor effects that were similar to the currently used (and incredibly expensive) immunotherapy.[ref] A 5-year mortality study in colon cancer patients showed that GLP-1 RA use decreased mortality risk by 60% in obese patients.[ref] Animal studies may show the mechanism

They mimic the natural hormone GLP-1, which: Stimulates insulin secretion Suppresses glucagon (a hormone that raises blood sugar) Delays gastric emptying (keeping you full longer) Reduces appetite via brain satiety centers This combination of effects leads to significant weight loss, improved blood sugar control, and reduced cardiovascular risks, especially when combined with lifestyle and plant-based care