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5 Additionally, the kidney excretes the excess conjugated bilirubin from the serum, leading to an increased amount of urinary coproporphyrin excretion (as discussed below), with dark urine as a result

FDA-labeled warnings for these medications include acute pancreatitis , acute kidney injury from dehydration, acute gallbladder disease (including cholecystitis and cholelithiasis), and intestinal obstruction

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If tubing has been removed from package and used, please dispose of it after 4 days, regardless of continued use.

It often happens because the medication slows down gastric emptying (how fast food leaves the stomach)