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Description

The formation of new blood vessels is often insufficient to provide adequate oxygen to the synovium, leading to a decrease in local microenvironmental oxygen tension and the formation of a hypoxic synovial microenvironment, which in turn affects angiogenesis, inflammatory responses, matrix degradation, cartilage erosion, energy metabolism disorders, and oxidative stress (126, 127)

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The images were processed using the software FLIR ResearchIR MAX (4.40.12.38), and the mean temperature of brown adipose tissue area was represented

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2026 Feb 12;19(2):309

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