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Arteries and veins lose their elasticity, leading to increased vascular stiffness, which can result in higher blood pressure and a higher risk of cardiovascular diseases

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That overlap could account for the lower GLP-1 addiction risk observed across the study population

However, the potential for delaying or preventing the progression of T2DM in patients treated with GIP and GLP-1 remains uncertain, as there is currently no definitive evidence from human studies demonstrating that enhanced incretin activity directly affects -cell mass or alters the progressive loss of insulin secretory capacity in humans