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Description

CagriSema vs Tirzepatide (REDEFINE 4): strong weight loss, but an important endpoint miss Novo Nordisk has announced headline results from the open-label phase 3 REDEFINE 4 trial comparing CagriSema (cagrilintide + semaglutide) vs tirzepatide 15 mg in obesity

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Lancet 398 , 6477 (2021)

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Dysregulation of LDL receptor under the influence of inflammatory cytokines: a new pathway for foam cell formation

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Both are complementary in multi-tissue protocols, with non-redundant mechanisms

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Maintain a balanced diet to complement supplementation

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