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Crash dieting or extreme calorie restriction can result in a lack of essential nutrients, leading to hair thinning and shedding, often due to conditions like telogen effluvium
In additional experiments with glioblastoma cells placed in the brain, they used a drug to block androgen signaling in males that had not been castrated or gave testosterone back to males that were castrated
Reviews of human pharmacokinetics consistently describe 7-OH as a minor metabolite formed in the body, not a major constituent
