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Figure 6 Statements Author contributions All authors listed, have made substantial, direct, and intellectual contribution to the work, and approved it for publication

Media description (scene 4): The number on the scale climbs until it reaches 320

Any unexplained weight loss beyond what is expected from the medication's therapeutic effect, or symptoms suggesting malabsorption such as pale, floating, foul-smelling stools, require investigation to exclude pancreatic or other gastrointestinal pathology

Available in a pen or vial, tirzepatide is injected subcutaneously (under the skin) into the abdomen, thigh, or upper arm

Abstract During type 1 diabetes (T1D), oxidative stress in beta cells may cause early beta cell dysfunction and initiate autoimmunity