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Anxiety typically involves a psychological component, such as worry, fear, or a sense of impending doom, alongside the physical symptoms

Histone deacetylases (HDACs), in particular, have emerged as key regulators of astrocyte-mediated neuroinflammation and neurodegeneration

It is described as being several times more powerful than synephrine and other amines like octopamine that can be naturally found in citrus extracts

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Neuroscience (2015) 294:15665.10.1016/j.neuroscience.2015.03.010 55 IwaiTJinKOhnukiTSasaki-HamadaSNakamuraMSaitohAet alGlucagon-like peptide-2-induced memory improvement and anxiolytic effects in mice