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Given the stable HRs across the spectrum of frailty, these differences in number needed to treat between frail and non-frail people are primarily driven by the higher number of events among frail patients, which highlights the greater vulnerability of this population. Lower CV risk with SGLT2 inhibitors vs

GLP-1 is a hormone associated with appetite regulation and insulin response and is the target of several FDA-approved prescription medications.

Multiple lipid species were decreased in both surgical groups at 30 minutes, consistent with postprandial rises in insulin secretion

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