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in vivo studies (animal models): It's absolutely paramount to consult existing scientific literature, particularly peer-reviewed articles, specific to your chosen model and research question

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A prespecified analysis of pooled data from the STEP-HFpEF and STEP-HFpEF DM trials demonstrated that significantly more patients treated with Wegovy 2.4 mg SC once weekly had an improvement of at least one in New York Heart Association (NYHA) functional class compared to those who received placebo (32.6% versus 21.5%, respectively

The mice were raised in standard environment with a temperature of 23-25 C and a 12-hour light-dark cycle and provided food and water ad libitum