aod9604 clinical trial obesity Pharmacotherapy: Current Perspectives and Future Directions Inside the Science of AOD

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Mechanisms: Activates beta-3 adrenergic receptors to enhance fat breakdown without affecting muscle or bone metabolism

This small molecule works by selectively inhibiting nicotinamide N-methyltransferase (NNMT), an enzyme that plays a crucial role in cellular energy metabolism and fat storage regulation [1]

The sixth coordination site, the reactive center, is variable, being a cyano group (CN), a hydroxyl group (OH), a methyl group (CH 3 ) or a 5-deoxyadenosyl group

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