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Transcobalamin II Antibodies Hereditary illnesses and the long-term use of B12 injections can sometimes trigger the production of antibodies that work against transcobalamin II, leading to the vitamin not being utilised properly (9)

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Main Phase (Baseline to Week 26): Study 1 (NCT 00123253) This study randomized 412 HIV-infected patients with lipodystrophy and excess abdominal fat to receive either a 2 mg dose of EGRIFTA (1 mg/vial formulation) (N=273) or placebo (N=137)

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Neurologic manifestations will not be prevented with folic acid, and if not treated with vitamin B 12, irreversible damage will result