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Sleep problems are recognised menopause symptoms by the NHS: Sleep problems in menopause (NHS)

Changes in sleep Sermorelin can affect your sleep patterns since it influences growth hormone release, which is closely linked to sleep cycles

reported that in early stage of menopause (particularly less than five years after menopause), the proinflammatory cytokines levels in the serum were increased and return to the normal levels in the late stage, with values parallel to pre menopause phase [26]

Its worth noting that weight loss and changes in diet can also play a role in mood changes