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A 30mg vial at 8mg per week lasts about 3.75 weeks

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Patients with glutathione synthetase deficiency accumulate the dipeptide -glutamylcysteine and cysteine in fibroblasts [24]

Moreover, compromised intestinal barrier integrity and gut-derived microbial components such as LPS activate TLR/NF-B/NLRP3 pathways, which not only drive systemic inflammation but also modulate gut-derived tryptophan metabolism and serotonin synthesis, thereby coupling immune regulation with neuromodulatory functions