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Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for type 2 diabetes management (under the brand names Ozempic and Rybelsus) and chronic weight management (under the brand name Wegovy)

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The medication class was not studied extensively in pregnant populations because pregnancy is generally an exclusion criterion in clinical trials

After 1 year of treatment, the average weight loss with semaglutide was 14.6 kg, or 14.1% of body weight, while the average weight loss with Tirzepatide was 17.2 kg, or 16.5% of body weight

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