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Moreover, zinc was shown to promote mitochondrial function through SIRT3Mfn2-mediated pathways in microglialneuron systems, indicating the precise modulation of organellar metabolism 155

GLP-1 acts on the GLP-1R, activating multiple intracellular signaling pathways, including the cAMP/PKA pathway, the PI3K/Akt signaling pathway, and pathways related to anti-inflammatory and anti-oxidative stress responses, among others

In disorders such as thalassemia and sickle cell anemia, this is clearly visible