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Before this meta-analysis, the IM route was generally the preferred route, but our results showed that no route is usually preferred, and SL and oral routes should be considered comparable alternative routes

In this study, sound therapy was the most commonly used treatment, and other coping practices included diverting attention, relaxation, meditation, yoga, and physical activity

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Its half - life is also relatively brief, on the order of a few minutes to half an hour in the bloodstream