Stomach acid and digestive enzymes are designed to break down proteins, and since glutathione is a tripeptide (a small protein), the body often digests it into its three base amino acids before it ever reaches the liver
This is also why a secretagogue approach is framed as "axis-friendly": because endogenous somatostatin is still in the loop, negative feedback is preserved, which in principle restrains the supraphysiologic IGF-1 spikes seen with exogenous GH
Yes, but with medical oversight
Twenty-seven programs are racing into a category where the mechanism is known, the readouts are imminent, and the market is larger than any drug class that has ever come before
however, knowing this, empowers us to create a common sense anti-aging strategy that promotes optimum levels of glutathione throughout our life