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So, in vitro cultures of mouse mGLUTag L cells (37, 38) and mouse assays (38) revealed that palmitate is a key factor affecting L cells as well as eliminating GLP-1 secretion rhythms, even at non-obesogenic doses, interfering with CLOCK : BMAL1 transcriptional activity, increasing Bmal1 transcriptional repression

Read the full JDD article for detailed methods and results and consider whether this evidence raises clinical questions worth exploring in your practice or research on hidradenitis suppurativa