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Understanding their potential disease-modifying effects on the inflamed synovium is essential to determine whether these therapies could alter the trajectory of OA rather than solely improve symptoms

Research (primarily in animal models) has shown potential effects such as: Supporting soft tissue repair (muscle, tendon, ligament) Promoting angiogenesis (formation of new blood vessels) Supporting gastrointestinal integrity and mucosal protection Modulating inflammatory responses While these findings are promising, clinical research in humans remains limited, and results should be interpreted with caution

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