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Cahill, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, and colleagues, therefore, aimed to compare rates of asthma exacerbations and symptoms between adults with type 2 diabetes and asthma prescribed GLP-1R agonists and those prescribed SGLT-2 (sodiumglucose cotransporter-2) inhibitors, DPP-4 (dipeptidyl peptidase-4) inhibitors, sulfonylureas, or basal insulin for diabetes treatment intensification

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Individual receptor sensitivity, baseline insulin resistance, genetic polymorphisms in GLP-1 and GIP receptors, and prior treatment duration all affect response