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Common dose-limiting side effects include severe nausea, constipation, dehydration, and loss of appetite that becomes problematic rather than therapeutic

Study 1 enrolled 3,731 patients with obesity (BMI greater than or equal to 30 kg/m2) or with overweight (BMI 27-29.9 kg/m2) and at least one weight-related comorbid condition such as treated or untreated dyslipidemia or hypertension

Furthermore, both obesity and male sex have been independently associated with elevated hematological parameters (25, 26)

Influence of N-Acetylcysteine Supplementation on Physical Performance and Laboratory Biomarkers in Adult Males: A Systematic Review of Controlled Trials

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