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677 Ketamine also exhibits neuroprotective effect in alleviating oxidative stress after TBI through the activation of Nrf2

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Given that GLP-1 936 amide is the major circulating form of GLP-1 post-prandially and is a low affinity weak partial agonist or antagonist at the GLP-1R, we investigated interaction between this metabolite and compound 2 in a cell line with recombinant expression of the human GLP-1R and the rat insulinoma cell line, INS-1E, with native expression of the GLP-1R

3A) was confirmed in an agarose gel to assess the electrophoretic retardation, and we used four N/P ratios: 1:0.5, 1:1, 1:1.5 and 1:2 (Figs