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(1999) demonstrated the wound-healing effects of TB-500, already known for its angiogenic properties

It was hypothesized during this investigation that these components might be somatomedins, leading to the designation of these compounds as insulin-like growth factors. (1) Further explorations into the insulin-like growth factors involved gene-targeting approaches to potentially enhance their bioavailability and potency

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The actual choice of antioxidant therapy is it xenobiotic or endogenous, should be indicated based on sound molecular knowledge of the involvement of oxidative stress in the actual pathology