These commonly include: Nausea often the most reported symptom, typically mild to moderate Vomiting less common but possible, particularly after eating too quickly or too much Diarrhoea or constipation bowel habit changes are frequently noted Bloating and indigestion a sensation of fullness or discomfort after meals Fatigue some patients report low energy levels in the early weeks These effects are generally transient and tend to improve as the body adapts to the medication
Patients with certain FTO or MC4R profiles may respond better to evening injections that align with their natural appetite peaks, while strong GLP1R responders often succeed with morning or evening timing equally
Personalized Protocol Medication selection, starting dose, titration schedule, and nutrition guidance built around your results
Semaglutides benefits are particularly pronounced when compared to other GLP-1 receptor agonists like liraglutide, as it offers greater efficacy over similar treatment durations, resulting in more substantial weight reduction
Semaglutide British National Formulary