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For some people, this works well

In double-blind, placebo-controlled trials, daily application of GHK-Cu cream at 3% concentration for 12 weeks produced a 70% increase in skin collagen thickness as measured by ultrasound imaging, a 40% increase in skin elasticity, and visible reduction in fine lines and wrinkles

Quad-agonists and even more complex multi-receptor compounds are already in preclinical development

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AOD 9604 users who report positive results typically notice changes after 4 to 8 weeks of daily use, primarily in stubborn fat areas