If your primary goal is more significant weight loss or you have established cardiovascular disease, Wegovy is typically the stronger option
Most providers follow the same FDA-based baseline: Obesity (BMI 30) or overweight (BMI 27) with at least one weight-related comorbidity, such as hypertension, type 2 diabetes, prediabetes, dyslipidemia, or obstructive sleep apnea
Swimming is particularly beneficial as it provides movement without joint stress
GLP-1 agonists showed a higher reduction of HbA1c compared to placebo when including only obese patients, MD -0.60, 95% CI , -1.06--0.13
These agents promote natriuresis, reduce intravascular volume and triglyceride levels, and lower blood pressure, changes that enhance myocardial energy efficiency and overall hemodynamics [81,82,83]