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Ultimately, the safe and effective use of bupropion and Saxenda in combination requires individualised medical assessment, careful monitoring, and collaborative decision-making between patient and healthcare provider

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A.Deschnes-SimardX.RamanathanS.GagnonJ.MooresA.et al (2009)

Unexpectedly, patients began shedding weight while using them, sparking interest in their potential for weight loss

The good news is that early evidence on oral semaglutide suggests a potential advantage here: One study showed that oral semaglutide improved blood sugar and reduced body fat while not significantly affecting muscle mass in those with type 2 diabetes