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Vitiligo is considered a relatively common skin condition, affecting about 1% of the global population

And again two weeks after that

This breakdown is typically associated with the disintegration of collagen fibers, frequently resulting from either tissue damage or the natural degradation process

MeRIP- qRT-PCR For the fragmentation of 10 g of sample RNA, 1 L of the 10X Fragmentation Buffer (Invitrogen, AM8740) was added to the 10 L RNA sample

Specifically, SIRT3 deacetylates and inhibits aldehyde dehydrogenase 2, which prevents the conversion of acetaldehyde to acetate, potentially leading to acetaldehyde toxicity 183