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In mice, the drug led to significant weight loss and reduced side effects

They remove metabolic bottlenecks rather than directly burning calories

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doi: 10.1016/j.redox.2024.103255 60 JiangQWanRJiangJLiTLiYYuSet al

In addition to the beneficial effect of GLP-1RA on hepatic steatosis, given that the most serious risk of death from NAFLD is cardiovascular disease, the findings indicating GLP-1RA is superior to TZD in reducing cardiometabolic risk parameters such as BMI and WC further emphasize the favorable role of GLP-1RA in the treatment of NAFLD [10]