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Serum samples were assayed for general clinical chemistry markers [i.e., glucose, total protein, blood urea nitrogen (BUN), creatinine, BUN/creatinine ratio, uric acid, aspartate aminotransferase (AST), alanine aminotransferase (ALT), creatine kinase (CK), lactate dehydrogenase (LDH), gamma glutamyl transferase (GGT), albumin, globulin, sodium, chloride, calcium, carbon dioxide, total bilirubin, alkaline phosphatase, triglycerides, cholesterol, high density lipoprotein (HDL), and lower density lipoprotein (LDL)]

On the other hand, the T-to-C substitution at GCLC rs1555903 leads to higher GCLC gene expression, as shown in a small set of kidney cortex samples (N = 73, = 0.73, P = 0.008) from the Genotype-Tissue Expression (GTEx) dataset 30

10.1111/j.1749-6632.1993.tb39148.x