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When evaluating the differences in the construction of the NALFD/NASH model between the two methods, it was found that the MCD diet could spontaneously lead to liver fibrosis within 24 weeks and significantly affect the expression of genes involved in liver fibrosis pathways

Neurologic symptoms of pellagra include headache, fatigue, apathy, depression, ataxia, poor concentration, delusions, and hallucinations, which can lead to confusion, memory loss, psychosis, and eventual death (27)

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H., Ramos, P

Although the signaling pathways leading to the progression of apoptosis have been extensively characterized, recent studies highlight the regulatory role of changes in the intracellular milieu (permissive apoptotic environment) in the efficient activation of the cell death machinery