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This regulation impacts stomatal function, with GPX3-mediated ABA signaling inducing stomatal closure to prevent pathogen entry while potentially increasing susceptibility post-invasion by weakening cell wall defenses (Melotto et al., 2006

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doi: 10.3389/fimmu.2015.00151 177 BlomABBrockbankSMvan LentPLvan BeuningenHMGeurtsJTakahashiNet al

These uses may have the backing of plausible mechanistic rationales, but none possess the robust clinical validation I would want to see in a proven protocol

Some common side effects include nausea, diarrhea, and reduced appetite, which typically subside over time