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These findings demonstrated that ZXGD can reverse augmented proliferation and apoptosis resistance of PASMCs through modulating caspase 3, caspase 8, caspase 9, Bax, Bcl 2 and PCNA in vitro, indicated the therapeutic potential of ZXGD for alleviating pulmonary vascular remodeling

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Added in vitro, thymulin decreased the peak of TNF- production in macrophages cultivated with LPS