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In PD, systemic iron accumulation contributes to striatal dopamine depletion, loss of neuromelanin, and the formation of intracellular Lewy bodies, which are primarily composed of aggregated -syn
USA 106 , 50705075 (2009)
Uversky et al., 2000a
These patients exhibit a greater GH secretory capacity than normal subjects, probably caused by a diminished tone in the IGF-1 sustained negative feedback control exerted upon somatotroph responsiveness
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