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Given that TBI remains an area of significant unmet clinical need, these preclinical findings have positioned BPC-157 as a candidate worth further investigation in neurotrauma research

These include dopamine leakage from synaptic vesicles, an increased rate of dopamine conversion to DOPAL due to upregulated monoamine oxidase, and a decrease in DOPAL degradation caused by aldehyde dehydrogenases

Its copper-chelating properties and documented interaction with the extracellular matrix make it a reference compound for researchers studying metallopeptide biology and connective tissue signalling

& Fabritiis, G