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Besides lowering glucose, GLP-1RAs have beneficial effect on heart, brain, and pancreas, according to an international team that conducted the semaglutide trial

Allergic reactions: Signs of an allergic reaction, including rash, itching, swelling (especially of the face, tongue, or throat), severe dizziness, or difficulty breathing, require emergency medical attention

If you have diagnosed panic disorder, I would pick tirz, it is not a known documented interaction, but I have seen 2 or 3 people on this forum with panic episodes from reta, so while rare and not documented in the scientific literature as far as I know, it is possible it could trigger them in those with the right susceptibility