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GLP-1s work by activating GLP-1 receptors, which leads to the following effects [7,8]: Increased insulin production Reduced glucagon release Reduced appetite Delayed gastric emptying Researchers are still investigating how GLP-1s cause weight loss

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Hardie LJ, Briggs JA, Davidson LA, Allan JM, King RF, Williams GI, Wild CP

The l-EV and s-EV fractions were collected from HEK293 cells transfected with these constructs using differential centrifugation