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335,336 PI3K acts as an intrinsic negative regulator of interleukin 12 (IL-12) production in response to TLR signaling, thereby limiting excessive Th1 polarization

doi: 10.1152/physiolgenomics.00127.2010 251 HumbyFDurezPBuchMHLewisMJRizviHRivelleseFet al

Future study should seek to describe characteristics which may predispose patients to a fulsome treatment response, as well as assessing the clinical utility and feasibility of this therapy in a real-world setting

Editorial Advisory Board Member, Harvard Health Publishing As the adage goes, the eyes are the windows to the soul