On three visits (before, 3 months in, and after 6 months of supplementation), subjects exercised for 30 min on a low intensity (50% Wmax), 30 min on a higher intensity (80% Wmax), and finally performed a 30 min all-out time trial test
The Importance of Diet and Counseling
Open questions include how various salt forms form volatile amines under heat and humidity, and whether common flavoring or acidity adjustments accelerate or slow odor development
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This allows researchers to test a range of doses on a smaller cohort, identifying the minimum effective dose and any potential adverse effects before committing to a larger, more resource-intensive study