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On metabolic secondary endpoints (LDL, prediabetes reversal, possibly OA pain), retatrutide has signals no other compound in the class has produced

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In light of these studies, we want to remind patients and healthcare providers that while GLP-1 drugs can be effective for weight loss, they may come with unintended consequences," said Elaine Shi, Co-CEO at BodySpec

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Retatrutide is an investigational triple-hormone receptor agonist that mimics the biological effects of GLP-1, GIP, and glucagon, under investigation for its role in blood glucose regulation and weight modulation

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Patients with severe gastrointestinal disease , including gastroparesis, may not tolerate these medicines well due to their effect on gastric emptying

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