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The searches were conducted in adherence to the PRISMA-S guidelines, and were restricted to human studies conducted in August 2024, without any language and date restrictions, unless specified

Additional information Peer review information Nature Communications thanks Radostin Danev, Kyle Sloop and other, anonymous, reviewers for their contributions to the peer review of this work

In normal pancreas, pancreatic cells expressed GLP-1R, with only low expression in acinar cells, whereas in AP or CP, acinar cells, ductal cells and activated PSCs expressed GLP-1R

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