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All enzymatic systems show more enhanced activity in the population without Down syndrome than in the children with Down syndrome, however, there was no statistically significant difference between the two groups

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Cost Optimization Strategies GHK-Cu costs add up over extended protocols, particularly at higher doses or daily frequency

Intracranial hemorrhage can be observed in moderate to severe cases

Ethics declarations Competing interests RS and JPR received research funding for this study from Researched Nutritionals, LLC